Bringing chemistry to medicine to redefine the undruggable

Chemical approaches, such as those that leverage induced proximity, targeted degradation, synthetic gene regulators or protein design offer opportunities to therapeutically target cellular processes that have long been thought of as undruggable. We report on the progress and the potential for transf...

Full description

Saved in:
Bibliographic Details
Published inNature chemical biology Vol. 20; no. 7; pp. 807 - 809
Main Authors Deane, Caitlin D, Fischer, Marcus, Shelat, Anang A
Format Journal Article
LanguageEnglish
Published United States Nature Publishing Group 01.07.2024
Subjects
Biology
Cancer therapies
Chemistry
Collaboration
Conferences
Drug therapy
Enzymes
Epigenetics
Families & family life
Liver cancer
Medicine
Pediatrics
Proteins
Transcription factors
Tumors
Online AccessGet full text

Cover

More Information
Summary:Chemical approaches, such as those that leverage induced proximity, targeted degradation, synthetic gene regulators or protein design offer opportunities to therapeutically target cellular processes that have long been thought of as undruggable. We report on the progress and the potential for transformative collaborations between fields discussed at the 2023 Bringing Chemistry to Medicine symposium at St. Jude Children’s Research Hospital.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1552-4450
1552-4469
1552-4469
DOI:10.1038/s41589-024-01598-1