Transcatheter therapies for arrhythmias in patients with complex congenital heart disease

Arrhythmias are responsible for significant morbidity and mortality in patients with complex congenital heart disease (CHD). Pharmacologic antiarrhythmic therapy often proves ineffective or intolerable due to adverse side effect profile in a patient group consigned to lifelong treatment. Interventio...

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Bibliographic Details
Published inInterventional cardiology Vol. 7; no. 2; pp. 199 - 215
Main Authors Grant, Elena K, Berul, Charles I
Format Journal Article
LanguageEnglish
Published London Future Medicine Ltd 01.04.2015
Subjects
ablation
Antiarrhythmia agents
Arrhythmia
Care and treatment
Complications and side effects
Congenital heart defects
congenital heart disease
electrophysiology
Health aspects
Risk factors
United States
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Summary:Arrhythmias are responsible for significant morbidity and mortality in patients with complex congenital heart disease (CHD). Pharmacologic antiarrhythmic therapy often proves ineffective or intolerable due to adverse side effect profile in a patient group consigned to lifelong treatment. Interventional electrophysiology procedures have revolutionized arrhythmia management in the CHD population since the introduction of transcatheter ablation in the late 1980s. Tremendous advances in electroanatomic mapping and ablation technology have led to increased procedural success in conjunction with a dramatically reduced risk profile to overcome the challenges of patient size, abnormalities of the intrinsic conduction system, mapping of arrhythmia in complex congenital cardiac malformations and limited access to surgically isolated cardiac chambers. Future interventional electrophysiology innovations are geared to provide further reduction in radiation exposure for the CHD population.
ISSN:1755-5302
1755-5310
DOI:10.2217/ica.15.3