Endotoxins of gram-negative anaerobic bacteria

The author reviews the data available on endotoxins of Fusobacterium, Sphaerophorus, Leptotrichia, and Veillonella species, and reports his own findings with lipopolysaccharides extracted from Bacteroides fragilis strains by the trichloroacetic acid method. The latter extracts showed a very low toxi...

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Bibliographic Details
Published inInfection Vol. 8 Suppl 2; p. S138
Main Author Grehn, M
Format Journal Article
LanguageEnglish
Published Germany 01.01.1980
Subjects
Animals
Bacteroides - pathogenicity
Endotoxins - isolation & purification
Endotoxins - toxicity
Gram-Negative Anaerobic Bacteria - analysis
Gram-Negative Anaerobic Bacteria - pathogenicity
Lipopolysaccharides - isolation & purification
Mice
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Summary:The author reviews the data available on endotoxins of Fusobacterium, Sphaerophorus, Leptotrichia, and Veillonella species, and reports his own findings with lipopolysaccharides extracted from Bacteroides fragilis strains by the trichloroacetic acid method. The latter extracts showed a very low toxicity for mice after i.v. injection of dosages of less than or equal to 500 micrograms and a slight leucopenic effect in mice after intraperitoneal injection of 50 micrograms.
ISSN:0300-8126
1439-0973
DOI:10.1007/BF01639872