Blood levels and half-life of methylmethacrylate after tourniquet release during knee arthroplasty

The blood levels and the half-life of monomeric methylmethacrylate after tourniquet release were studied in nine patients with osteoarthrosis or rheumatoid arthritis of the knee joint, treated with the Townley prosthesis under spinal anesthesia. Several ventricular extrasystoles were monitored in on...

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Bibliographic Details
Published inArchives of orthopaedic and traumatic surgery Vol. 105; no. 1; p. 36
Main Authors Svartling, N, Pfäffli, P, Tarkkanen, L
Format Journal Article
LanguageEnglish
Published Germany 1986
Subjects
Aged
Bicarbonates - blood
Blood Pressure
Bone Cements
Carbon Dioxide - blood
Colloids
Female
Half-Life
Heart Rate
Humans
Hydrogen-Ion Concentration
Knee Prosthesis - adverse effects
Knee Prosthesis - methods
Male
Methylmethacrylate
Methylmethacrylates - blood
Middle Aged
Oxygen - blood
Tourniquets
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Summary:The blood levels and the half-life of monomeric methylmethacrylate after tourniquet release were studied in nine patients with osteoarthrosis or rheumatoid arthritis of the knee joint, treated with the Townley prosthesis under spinal anesthesia. Several ventricular extrasystoles were monitored in one patient with high blood levels of monomeric methylmethacrylate (119.80 micrograms/ml). The blood levels of monomeric methylmethacrylate ranged between 0.10 and 1.44 microgram/ml in the rest of the patients. The half-life of monomeric methylmethacrylate in vivo was 47-55 min.
ISSN:0344-8444
DOI:10.1007/BF00625658