A New Noroleanane from the Seeds of Trichosanthes kirilowii

A new noroleanane named as karounitriol (1), together with four known compounds, 7-oxodihydrokarounidiol (2), isokarounidiol (3), karounidiol (4), and stigmasta-7,22-dien-3β-ol were isolated from the seeds of Trichosanthes kirilowii Maxim. Structure of the new compound was elucidated as 3α,7β,29-tri...

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Bibliographic Details
Published inNatural product communications Vol. 13; no. 7
Main Authors Xu, Liang, Tang, Chun-Feng, Wu, Cui, Ma, Yu-Cui, Chao, Zhi-Mao
Format Journal Article
LanguageEnglish
Published Los Angeles, CA SAGE Publications 01.07.2018
Subjects
Noroleanane
Pentacyclic triterpene
Karounitriol
Trichosanthes kirilowii
Cucurbitaceae
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Summary:A new noroleanane named as karounitriol (1), together with four known compounds, 7-oxodihydrokarounidiol (2), isokarounidiol (3), karounidiol (4), and stigmasta-7,22-dien-3β-ol were isolated from the seeds of Trichosanthes kirilowii Maxim. Structure of the new compound was elucidated as 3α,7β,29-trihydroxy-D:C-friedo-olean-8-ene on the basis of spectroscopic methods including extensive 1D NMR (1H, 13C), 2D NMR (1H-1H COSY, DEPT, HMQC, HMBC, and NOESY), IR, and MS studies.
ISSN:1934-578X
1555-9475
DOI:10.1177/1934578X1801300707