Differential cell motion: A mathematical model of anterior posterior sorting

• Published in: Biophysical journal Vol. 122; no. 21; pp. 4160 - 4175
• Main Authors: Song, Joy, Evans, Emily J., Dallon, J.C.
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 07.11.2023

Here, we investigate how a subpopulation of cells can move through an aggregate of cells. Using a stochastic force-based model of Dictyostelium discoideum when the population is forming a slug, we simulate different strategies for prestalk cells to reliably move to the front of the slug while omitti...