Cytogenetic findings in T-zone lymphoma

Five cases of T-zone lymphoma were investigated with histologic, immunologic, and cytogenetic methods. The chromosome analyses were performed on lymphoma cells prepared immediately after removal of the lymph nodes. The chromosomes involved in structural rearrangements were nos. 1, 2, 3, 4, 14, and Y...

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Bibliographic Details
Published inJournal of cancer research and clinical oncology Vol. 101; no. 1; p. 81
Main Authors Gödde-Salz, E, Schwarze, E W, Stein, H, Lennert, K, Grote, W
Format Journal Article
LanguageEnglish
Published Germany 01.01.1981
Subjects
Aged
Chromosome Aberrations
Humans
Karyotyping
Lymphocytes - immunology
Lymphocytes - ultrastructure
Lymphoma - immunology
Lymphoma - pathology
Male
Middle Aged
T-Lymphocytes - pathology
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Summary:Five cases of T-zone lymphoma were investigated with histologic, immunologic, and cytogenetic methods. The chromosome analyses were performed on lymphoma cells prepared immediately after removal of the lymph nodes. The chromosomes involved in structural rearrangements were nos. 1, 2, 3, 4, 14, and Y. Numbers 3, 5, 6, and 13 were lost by some tumors, and nos. 3 and 9 were gained. Chromosome 3 was involved most often in structural and numerical aberrations, whereas 14q + markers occurred in only one case. The importance of multidisciplinary studies is pointed out.
ISSN:0171-5216
1432-1335
DOI:10.1007/BF00405068