An assessment of a collagen/vicryl composite membrane to repair defects of the urinary bladder in rabbits

Collagen/vicryl (Polyglactin) composite membrane has been used to repair full-thickness defects in the urinary bladder of rabbits. The material has been shown to be biodegradable, prevent leakage of urine, and is readily replaced by collagenous scar tissue lined with a urothelium. Regeneration of sm...

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Bibliographic Details
Published inUrological research Vol. 15; no. 4; p. 235
Main Authors Monsour, M J, Mohammed, R, Gorham, S D, French, D A, Scott, R
Format Journal Article
LanguageEnglish
Published Germany 01.08.1987
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Summary:Collagen/vicryl (Polyglactin) composite membrane has been used to repair full-thickness defects in the urinary bladder of rabbits. The material has been shown to be biodegradable, prevent leakage of urine, and is readily replaced by collagenous scar tissue lined with a urothelium. Regeneration of smooth muscle has been observed in the repair area of some animals. The results suggest that such a material may well be of use to urologists wishing to augment contracted bladders or in the repair of bladder fistulae in human subjects, thereby avoiding the use of bowel or other material e.g. omentum.
ISSN:0300-5623
DOI:10.1007/BF00262106