The DNA sequence of a 7941 bp fragment of the left arm of chromosome VII of Saccharomyces cerevisiae contains four open reading frames including the multicopy suppressor gene of the pop2 mutation and a putative serine/threonine protein kinase gene

We report the sequence of a 7941 bp DNA fragment from the left arm of chromosome VII of Saccharomyces cerevisiae which contains four open reading frames (ORFs) of greater than 100 amino acid residues. ORF biC834 shows 100% bp identity with the recently identified multicopy suppressor gene of the pop...

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Bibliographic Details
Published inYeast (Chichester, England) Vol. 11; no. 8; p. 767
Main Authors Coglievina, M, Bertani, I, Klima, R, Zaccaria, P, Bruschi, C V
Format Journal Article
LanguageEnglish
Published England 30.06.1995
Subjects
Amino Acid Sequence
Chromosomes, Fungal
DNA, Fungal - chemistry
Genes, Fungal
Genes, Suppressor
Molecular Sequence Data
Mutation
Open Reading Frames
Protein-Serine-Threonine Kinases - genetics
Saccharomyces cerevisiae - genetics
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Summary:We report the sequence of a 7941 bp DNA fragment from the left arm of chromosome VII of Saccharomyces cerevisiae which contains four open reading frames (ORFs) of greater than 100 amino acid residues. ORF biC834 shows 100% bp identity with the recently identified multicopy suppressor gene of the pop2 mutation (MPT5); its deduced protein product carries an eight-repeat domain region, homologous to that found in the hypothetical regulatory YGL023 protein of S. cerevisiae and the Pumilio protein of Drosophila. ORF biE560 protein exhibits patterns typical of serine/threonine protein kinases, with which it shares high degrees of homology.
ISSN:0749-503X
DOI:10.1002/yea.320110808