Antenatal corticosteroids in COVID-19 perspective

The aim of this manuscript is to discuss the practice of antenatal corticosteroids administration for fetal maturation in severe acute respiratory syndrome coronavirus 2 positive pregnant women. Recent high-quality evidence supports the use of dexamethasone in the treatment of hospitalized patients...

Full description

Saved in:
Bibliographic Details
Published inWorld journal of experimental medicine Vol. 11; no. 4; pp. 37 - 43
Main Authors Vidaeff, Alex C, Aagaard, Kjersti M, Belfort, Michael A
Format Journal Article
LanguageEnglish
Published Baishideng Publishing Group Inc 20.09.2021
Subjects
Minireviews
Online AccessGet full text

Cover

More Information
Summary:The aim of this manuscript is to discuss the practice of antenatal corticosteroids administration for fetal maturation in severe acute respiratory syndrome coronavirus 2 positive pregnant women. Recent high-quality evidence supports the use of dexamethasone in the treatment of hospitalized patients with coronavirus disease 2019 (COVID-19). Randomized disease outcome data have identified an association between disease stage and treatment outcome. In contrast to patients with more severe forms who benefit from dexamethasone, patients with mild disease do not appear to improve and may even be harmed by this treatment. Therefore, indiscriminate usage of fluorinated corticosteroids for fetal maturation, regardless of disease trajectory, is unadvisable. Obstetrical care needs to be adjusted during the COVID-19 pandemic with careful attention paid to candidate selection and risk stratification.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
Corresponding author: Alex C Vidaeff, MD, Professor, Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Texas Childrens Hospital, Baylor College Medicine, 6651 Main St, Suite F1020, Houston, TX 77030, United States. vidaeff@bcm.edu
Author contributions: Vidaeff AC, Aagaard KM and Belfort MA contributed equally to this work and wrote the manuscript; all authors have read and approve the final manuscript.
ISSN:2220-315X
2220-315X
DOI:10.5493/wjem.v11.i4.37