Acute allergic reaction due to the administration of fibrinolytic therapy for ST-segment elevation myocardial infarction: case report and discussion

Although a rare phenomenon, acute allergic reactions to fibrinolytic and heparin therapy have been described in the literature. We report the case of a 63-year-old woman who experienced a severe anaphylactic reaction while undergoing fibrinolytic therapy with tissue plasminogen activator for an ST-s...

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Bibliographic Details
Published inCanadian journal of emergency medicine Vol. 5; no. 6; pp. 421 - 423
Main Authors Mills, Geoff C., Arntfield, Robert T., Sedran, Robert J.
Format Journal Article
LanguageEnglish
Published Cambridge, UK Cambridge University Press 01.11.2003
Springer Nature B.V
Subjects
Allergies
Case Report • Observations de cas
Drugs
Heart attacks
Heart disease
Physiological aspects
Treatment
allergic
heparin
fibrinolytic therapy
anaphylaxis
tPA
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Summary:Although a rare phenomenon, acute allergic reactions to fibrinolytic and heparin therapy have been described in the literature. We report the case of a 63-year-old woman who experienced a severe anaphylactic reaction while undergoing fibrinolytic therapy with tissue plasminogen activator for an ST-segment elevation myocardial infarction. Overall outcome was successful, but patient morbidity was increased because of the reaction and the subsequent therapy administered.
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ISSN:1481-8035
1481-8043
DOI:10.1017/S148180350000868X