Atorvastatin-Induced Necrotizing Myopathy and its Response to Combination Therapy
Atorvastatin is the most commonly used statin medication to decrease cholesterol levels and prevent atherosclerosis. Myopathy is a reported side effect of atorvastatin which can happen even after more than six months after starting the medication. The side effect on the muscle tissue can range from...
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Published in | Curēus (Palo Alto, CA) Vol. 13; no. 1; p. e12957 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Cureus
28.01.2021
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Subjects | |
Online Access | Get full text |
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Summary: | Atorvastatin is the most commonly used statin medication to decrease cholesterol levels and prevent atherosclerosis. Myopathy is a reported side effect of atorvastatin which can happen even after more than six months after starting the medication. The side effect on the muscle tissue can range from simple reversible myalgia to respiratory muscle compromise. Here we present a 46-year-old male who presented with myopathy after taking atorvastatin for two years. Biopsy proved immune-mediated necrotizing myopathy which responded to a combination of Rituximab and intravenous immunoglobulin therapy. |
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ISSN: | 2168-8184 2168-8184 |
DOI: | 10.7759/cureus.12957 |