Novel tributyl phosphate-based hydrophobic deep eutectic solvent: application in simultaneous liquid-liquid microextraction of parabens and their metabolite in surface water samples

A novel deep eutectic solvent (DES) with tributyl phosphate (TBP) as hydrogen bond acceptor and d , l -menthol (M) as hydrogen bond donor (HBD) was synthesized for the first time. M, a natural perfume, was selected as the HBD of the promising DES to tailor the extraction capacity and greenify the ex...

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Published inGreen chemistry : an international journal and green chemistry resource : GC Vol. 24; no. 2; pp. 85 - 813
Main Authors Cao, Jiangping, Liu, Yuwen, Zhao, Faqiong
Format Journal Article
LanguageEnglish
Published Cambridge Royal Society of Chemistry 18.10.2022
Subjects
Detection limits
Green chemistry
High performance liquid chromatography
Hydrogen bonds
Hydrophobicity
Liquid chromatography
Menthol
Metabolites
p-Hydroxybenzoic acid
Polarity
Solvents
Surface water
Water analysis
Water sampling
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Summary:A novel deep eutectic solvent (DES) with tributyl phosphate (TBP) as hydrogen bond acceptor and d , l -menthol (M) as hydrogen bond donor (HBD) was synthesized for the first time. M, a natural perfume, was selected as the HBD of the promising DES to tailor the extraction capacity and greenify the extraction solvent. The designed TBP-M (molar ratio 1 : 2)-based DES was applied in the simultaneous liquid-liquid microextraction (LLME) of a group of parabens (PBs) and their metabolite ( p -hydroxybenzoic acid, PHBA) with wide polarity range in surface water samples. The developed LLME was combined with high-performance liquid chromatography and showed low detection limits (0.5-0.9 μg L −1 ) and good linearity ( R 2 ≥ 0.9983), precisions (RSDs ≤ 7.6%) and recoveries (86.0% to 110%) under the optimum conditions. The presented procedure has the features of simplicity, inexpensiveness, effectiveness and reliability, and the novel DES has great potential in the highly effective and simultaneous extraction for compounds with different polarities such as PBs and PHBA in complex real water samples. Novel tributyl phosphate-based hydrophobic deep eutectic solvent: application in simultaneous liquid-liquid microextraction of parabens and their metabolite in surface water samples.
Bibliography:https://doi.org/10.1039/d2gc02097a
Electronic supplementary information (ESI) available. See DOI
ISSN:1463-9262
1463-9270
DOI:10.1039/d2gc02097a