CuO/Cu/rGO nanocomposite anodic titania nanotubes for boosted non-enzymatic glucose biosensors

• Published in: New journal of chemistry Vol. 47; no. 16; pp. 789 - 792
• Main Authors: Chahrour, Khaled M, Ooi, Poh Choon, Nazeer, Ahmed Abdel, Al-Hajji, Latifa A, Jubu, Peverga R, Dee, Chang Fu, Ahmadipour, Mohsen, Hamzah, Azrul Azlan
• Format: Journal Article
• Language: English
• Published: Cambridge Royal Society of Chemistry 24.04.2023
• Subjects: Aqueous solutions; Biosensors; Catalytic activity; Chemical elements; Copper; Copper oxides; Electrical measurement; Electrodes; Electrolytes; Glucose; Graphene; Metal foils; Nanocomposites; Nanoparticles; Nanotubes; Samplers; Titanium; Titanium dioxide
• ISSN: 1144-0546; 1369-9261
• DOI: 10.1039/d3nj00666b

Highly arranged porous anodic titania (TiO 2 ) nanotube arrays (ATNT) were fruitfully fabricated by the anodization of Ti foil in an ammonium fluoride electrolyte. Then, the CuO/Cu nanoparticles were consistently decorated onto the porous ATNT surface through electrochemical deposition and afterward impregnated into graphene oxide (GO) aqueous solution to produce CuO/Cu/GO-ATNT, which was then electrochemically reduced to form CuO/Cu/rGO nanocomposite ATNT electrode. The microstructures, morphologies, and chemical elements were investigated using XRD and FESEM techniques linked with EDS and XPS, respectively. The as-fabricated CuO/Cu/rGO nanocomposite ATNT electrode was utilized for non-enzymatic glucose sensing in a neutral electrolyte and exhibited superior electro-catalytic activity compared with the pristine and CuO/Cu nanoparticle ATNT electrodes. The electrocatalysis performance of the recommended CuO/Cu/rGO nanocomposite ATNT electrode was inspected and optimized. The experimental results exposed an effective amperometric electrode of glucose acquired under 0.6 V vs. Ag/AgCl with an excellent sensitivity of (371.6 μA mM −1 cm −2 ), a low detection limit (22.8 μM), and a wide linear range from 0.5 mM to 16 mM ( R 2 = 0.9992). This designed non-enzymatic glucose biosensor demonstrated high stability, reproducible, and selective biosensor. Hence, this endorses its promising technique for the detection of glucose samplers for clinical and pharmaceutical diagnoses. Highly arranged porous anodic titania (TiO 2 ) nanotube arrays (ATNT) were fruitfully fabricated by the anodization of Ti foil in an ammonium fluoride electrolyte.