Severe Shivering as an Adverse Effect of Regadenoson Myocardial Perfusion Imaging

Regadenoson myocardial perfusion imaging (MPI) is a widely used screening study for patients with an intermediate pretest probability of coronary artery disease (CAD). Via selective agonism of the adenosine A2A receptor, regadenoson can induce coronary steal, revealing stenotic vessel territory thro...

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Bibliographic Details
Published inCurēus (Palo Alto, CA) Vol. 13; no. 3; p. e14091
Main Authors Ahmad, Tanjeev, Linares, Juan, Valencia, Damian N, Agarwal, Ajay
Format Journal Article
LanguageEnglish
Published United States Cureus 24.03.2021
Subjects
Cardiology
Internal Medicine
cardiac stress testing
myocardial perfusion imaging
drug-related side effects and adverse reactions
regadenoson
shivering
mpi
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Summary:Regadenoson myocardial perfusion imaging (MPI) is a widely used screening study for patients with an intermediate pretest probability of coronary artery disease (CAD). Via selective agonism of the adenosine A2A receptor, regadenoson can induce coronary steal, revealing stenotic vessel territory through transient ischemia. Common side effects of this medication include chest pain, shortness of breath, nausea, vomiting, atrioventricular block, seizure, and allergic reactions. Here we present a case of severe shivering and chest tightness after the administration of regadenoson, along with a physiologic explanation and treatment.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.14091