A comprehensive review on transdermal patches as an efficient approach for the delivery of drug

In past years, various studies have considered transdermal drug delivery system for improving patient compliance. One approach to deliver drug via transdermal route is transdermal patch. These patches include single-layer drug in adhesive patches and micro reservoir transdermal patch & matrix sy...

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Bibliographic Details
Published inPolymer-plastics technology and engineering Vol. 63; no. 8; pp. 1045 - 1069
Main Authors Ashfaq, Ansa, Riaz, Tehseen, Waqar, Muhammad Ahsan, Zaman, Muhammad, Majeed, Imtiaz
Format Journal Article
LanguageEnglish
Published New York Taylor & Francis Ltd 23.05.2024
Subjects
Drug delivery systems
Irritation
Polyethylene glycol
Polymers
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Summary:In past years, various studies have considered transdermal drug delivery system for improving patient compliance. One approach to deliver drug via transdermal route is transdermal patch. These patches include single-layer drug in adhesive patches and micro reservoir transdermal patch & matrix system. Acrylic-acid, hydroxypropyl methylcellulose (HPMC) and polyethylene glycol are commonly used polymers for manufacturing of transdermal patches. Characterization of patches includes patch thickness, weight uniformity, irritation studies, in-vitro drug release and permeation studies. This review summarizes various polymers, types of transdermal patches and evaluation of transdermal patches based on up-to-date data extracted from reputed journals and official websites.
ISSN:2574-0881
0360-2559
2574-089X
1525-6111
DOI:10.1080/25740881.2024.2317408