Biopsychosocial risk factors for subjective cognitive decline among older adults during the COVID-19 pandemic: a population-based study

• Published in: Public health (London) Vol. 234; pp. 16 - 23
• Main Authors: Schrempft, S., Baysson, H., Graindorge, C., Pullen, N., Hagose, M., Zaballa, M.-E., Preisig, M., Nehme, M., Guessous, I., Stringhini, S., Arm-Vernez, I., Azman, A.S., Bachmann, D., Bal, A., Balavoine, J.-F., Barbe, R.P., Berthelot, J., Bouhet, A.R., Bryand-Rumley, G., Chappuis, F., Collombet, P., Coudurier-Boeuf, S., Courvoisier, D.S., de Mestral, C., D'ippolito, P., Dubos, R., Dumont, R., El Merjani, N., Flahault, A., Francioli, N., Harnal, S., Hurst, S., Kaiser, L., Kathari, G., Kherad, O., Lamour, J., Lescuyer, P., L'Huillier, A.G., Loizeau, A.J., Lorthe, E., Martinez, C., Mechoullam, S., Metral-Boffod, L., Noël, N., Pennacchio, F., Perez-Saez, J., Pittet, D., Posfay-Barbe, K.M., Poulain, G., Pugin, C., Richard, V., Rochat, D., Samir, K., Ramirez, H.S., Satin, E., Schaller, P., Semaani, C., Testini, S., Uppal, A., Urrutia-Rivas, D., Verolet, C., Vetter, P., Villers, J., Violot, G., Vuilleumier, N., Wisniak, A., Yerly, S.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.09.2024
• Subjects: Aged; Aged, 80 and over; Cognitive Dysfunction - epidemiology; Cohort Studies; COVID-19; COVID-19 - epidemiology; COVID-19 - psychology; Female; Humans; Male; Mental health; Older adults; Pandemics; Prevalence; Risk Factors; SARS-CoV-2; Subjective cognitive decline; Surveys and Questionnaires; Switzerland - epidemiology; Switzerland; COVID-19; Subjective cognitive decline; Older adults; Mental health
• ISSN: 0033-3506; 1476-5616; 1476-5616
• DOI: 10.1016/j.puhe.2024.05.025

There have been concerns that the COVID-19 pandemic and the measures used to contain it impacted the cognitive health of older adults. We therefore examined the prevalence of subjective cognitive decline, and its associated risk factors and health consequencs, among dementia-free older adults 2 years into the pandemic in Switzerland. Population-based cohort study. Prevalence of SCD was estimated using the cognitive complaint questionnaire administered to adults aged ≥65 years in June–September 2022 (Specchio-COVID19 cohort, N = 1414), and compared to prepandemic values from 2014 to 2018 (CoLaus|PsyCoLaus cohort, N = 1181). Associated risk factors and health consequences were assessed using logistic and/or linear regression. Prevalence of SCD in 2022 (18.9% [95% CI, 16.2–21.9]) was comparable to prepandemic levels in 2014–2018 (19.5% [17.2–22.1]). Risk factors included established risks for dementia–namely health issues, health behaviours, and depressive symptoms. Self-reported post-COVID, perceived worsening of mental health since the start of the pandemic, less frequent social club attendance, and increased loneliness were also risk factors for SCD. In turn, SCD was associated with poorer objective cognitive performance, difficulty performing instrumental activities of daily living, greater risk of falls, and lower well-being at one-year follow-up. While the overall prevalence of SCD in 2022 was comparable to prepandemic levels, we identified several pandemic-related risk factors for SCD, including perceived worsening of mental health and increased isolation since the start of the pandemic. These findings highlight the importance of mental health promotion strategies in reducing cognitive complaints and preventing cognitive decline.