Nurses' attitudes, behaviours, and enablers of intravenous to oral switching (IVOS) of antibiotics: a mixed-methods survey of nursing staff in secondary care hospitals across the Midlands region of England

• Published in: The Journal of hospital infection Vol. 150; pp. 9 - 16
• Main Authors: Hamilton, R.A., Williams, N., Ashton, C., Gilani, S.A.D., Hussain, S., Jamieson, C., Razaq, S., Jenkins, A.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.08.2024
• Subjects: Administration, Intravenous; Administration, Oral; Adult; Anti-Bacterial Agents - administration & dosage; Anti-Bacterial Agents - therapeutic use; Antimicrobial stewardship; Antimicrobial Stewardship - methods; Attitude of Health Personnel; England; Female; Humans; Intravenous antibiotic; Intravenous to oral switch; IVOS; Male; Middle Aged; Nurses; Nurses - psychology; Secondary Care; Secondary Care Centers - statistics & numerical data; Surveys and Questionnaires; Young Adult; England; Secondary care; Antimicrobial stewardship; IVOS; Intravenous antibiotic; Nurses; Intravenous to oral switch
• ISSN: 0195-6701; 1532-2939; 1532-2939
• DOI: 10.1016/j.jhin.2024.05.007

Intravenous (IV) antibiotic use in secondary care in England is widespread. Timely appropriate intravenous to oral switch (IVOS) has the potential to deliver significant clinical and operational benefits. To date, antimicrobial stewardship (AMS) efforts around IVOS have not focused on the nursing staff who administer antibiotics, which represents a significant gap in AMS programmes. To determine the involvement of bedside nurses in acute trusts in the Midlands region of England in IVOS in their organizations and describe their views regarding how to improve IVOS. An anonymous self-administered mixed-methods online survey was developed and distributed to nursing staff in acute trusts via antimicrobial stewardship networks between March and May 2023. Quantitative data was analysed to describe participant demographics and behaviours, whereas barriers and enablers to IVOS were explored through thematic content analysis of responses to open-ended questions. A total of 545 nursing staff responded to the survey. The majority (65.3%) routinely suggested IVOS to clinicians, despite only 50.6% being aware of local IVOS policies. One-third (34.7%) did not suggest IVOS, relying on doctors, believing their patients needed IV treatment, or lacked knowledge and skills to request IVOS. Content analysis of suggestions for improving the rate of IVOS proposed three major themes (People, Process, System) and identified that education and training, improved confidence and interprofessional relationships, and prompts were important drivers. Nursing staff suggest IVOS to other clinicians, but more education and resources are needed to enable and empower them in this role.