A concise enantioselective synthesis of iminosugar derivatives

The concise de novo synthesis of amino- and iminosugar derivatives is presented; the four stereocenters of the iminosugar derivatives are created in two-steps with high chemoselectivity and excellent enantioselectivity.

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Bibliographic Details
Published inChemical communications (Cambridge, England) no. 6; pp. 674 - 676
Main Authors Liao, WW, Ibrahem, Cordova, A
Format Journal Article
LanguageEnglish
Published CAMBRIDGE Royal Soc Chemistry 14.02.2006
Subjects
Catalysis
Chemistry
Chemistry, Multidisciplinary
Chromatography, High Pressure Liquid
Esters - chemistry
Imino Sugars - chemical synthesis
Models, Chemical
Physical Sciences
Science & Technology
Stereoisomerism
Sugar Acids - chemical synthesis
2-STEP SYNTHESIS
ALPHA-AMINO
ASYMMETRIC-SYNTHESIS
INHIBITION
DE-NOVO SYNTHESIS
ONE-POT
CROSS-MANNICH REACTION
ACID CATALYZED NEOGENESIS
ALDOL REACTIONS
SUGARS
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Summary:The concise de novo synthesis of amino- and iminosugar derivatives is presented; the four stereocenters of the iminosugar derivatives are created in two-steps with high chemoselectivity and excellent enantioselectivity.
ISSN:1359-7345
1364-548X
DOI:10.1039/b516352h