CdS/Mg-Fe layered double hydroxide: a versatile heterogeneous photocatalyst for the acylation of indoles with α-keto acids

• Published in: Green chemistry : an international journal and green chemistry resource : GC Vol. 26; no. 24; pp. 1234 - 1242
• Main Authors: Wang, Jun-Bo, Yue, Tong, Xu, Ling, Hao, Zhi-Qiang, Zhang, Zhan-Hui
• Format: Journal Article
• Language: English
• Published: Cambridge Royal Society of Chemistry 09.12.2024
• Subjects: Acylation; Air temperature; Catalytic activity; Hydroxides; Indoles; Iron; Irradiation; Magnesium; Oxidants; Oxidizing agents; Photocatalysis; Photocatalysts; Room temperature; α Radiation
• ISSN: 1463-9262; 1463-9270
• DOI: 10.1039/d4gc05239k

The CdS/Mg-Fe layered double hydroxide (LDH) was successfully constructed by coupling CdS and Mg-Fe LDH based on the mutually complementary properties of the two materials. This stable and recyclable heterogeneous photocatalyst was found to realize the C3-acylation of indoles with α-keto acids. The reactions were carried out under irradiation with blue light at room temperature using abundant and inexpensive air as the oxidant. This methodology gives easy access to 3-acyl indoles with high yields. CdS/Mg-Fe LDH can be recovered and reused for multiple runs without obviously losing its photocatalytic activity. The composite CdS/MgFe layered double hydroxide was constructed and confirmed as an efficient recyclable heterogeneous photocatalyst for C-3 acylation of indoles with α-keto acids under light irradiation at room temperature.