Synthesis and transformation of calcium carbonate polymorphs with chiral purine nucleotides

• Published in: New journal of chemistry Vol. 46; no. 47; pp. 22612 - 2262
• Main Authors: Iqbal, Muhammad Javed, Riaz, Muhammad Sohail, Talha, Khalid, Shoukat, Rizwan, Mahmood, Sajid, Ammar, Muhammad, Li, Hui
• Format: Journal Article
• Language: English
• Published: Cambridge Royal Society of Chemistry 05.12.2022
• Subjects: Adenosine triphosphate; Amino acids; Biomedical materials; Bionics; Calcite; Calcium carbonate; Crystal structure; Crystallization; Crystals; Dichroism; Morphology; Nucleotides; Optical properties; Pollution abatement; Spectrum analysis; Synthesis
• ISSN: 1144-0546; 1369-9261
• DOI: 10.1039/d2nj03813g

The biomineralization process in organisms produces better quality biominerals. The most promising approach is using proteins with differing amounts of amino acids in crystals to create biominerals. Calcium carbonate (CaCO 3 ) polymorph crystallization is controlled using the chiral nucleotides adenosine triphosphate (ATP) and guanosine triphosphate (GTP). SEM, XRD, TEM, FTIR spectroscopy, and chiral dichroism (CD) spectroscopy are utilized to study the crystals of CaCO 3 in detail. The results suggest that the purine nucleotides (ATP and GTP) lead to single cubic calcite crystals converted into spherical and sponge-like vaterite crystals. Chiral purine triphosphates influence the crystal structure and development of CaCO 3 significantly. ATP and GTP play a significant role in forming CaCO 3 polymorphs. The impacts of chiral ATP and GTP on vaterite production are also studied to understand better the diverse morphologies of vaterite originated and to introduce innovative ideas for developing biominerals into smart bionics. The synthesis of CaCO 3 with different chiral morphologies and polymorphs helps to generate materials like natural materials with enhanced optical properties and reflective properties, as found in living things. The synthesised CaCO 3 biomaterials with different crystal forms and morphologies may be used in ceramic, drug delivery, bone tissue, and pollution prevention applications. Crystallization of CaCO 3 polymorphs is controlled using the chiral purine nucleotides adenosine triphosphate (ATP) and guanosine triphosphate (GTP). The effects of ATP and GTP on the transformation of calcite into vaterite are investigated.