Light-induced inhibition of chymotrypsin using photocleavable monolayers on gold nanoparticles

Positively charged gold nanoparticles featuring photocleavable units within their surrounding monolayer are switched from non-interacting species to inhibitors of chymotrypsin through UV irradiation.

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Bibliographic Details
Published inChemical communications (Cambridge, England) no. 24; pp. 2866 - 2867
Main Authors Fischer, NO, Paulini, R, Drechsler, U, Rotello, VM
Format Journal Article
LanguageEnglish
Published CAMBRIDGE Royal Soc Chemistry 21.12.2004
Subjects
Chemistry
Chemistry, Multidisciplinary
Chymotrypsin - antagonists & inhibitors
Chymotrypsin - metabolism
Gold - chemistry
Molecular Structure
Nanostructures - chemistry
Photochemistry
Physical Sciences
Science & Technology
Spectrophotometry
Ultraviolet Rays
ROUTE
EXCITED-STATE
SURFACE RECOGNITION
P-HYDROXYPHENACYL
PROTEIN-PROTEIN INTERACTIONS
HIV-1 PROTEASE
RECEPTORS
ANTAGONISTS
CLUSTER
MOLECULES
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Summary:Positively charged gold nanoparticles featuring photocleavable units within their surrounding monolayer are switched from non-interacting species to inhibitors of chymotrypsin through UV irradiation.
Bibliography:Medline
NIH RePORTER
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1359-7345
1364-548X
DOI:10.1039/b408972c