Water-soluble poly( n -vinylamides)as a basis for the synthesis of polymeric carriers of biologically active compounds

• Published in: International journal of polymer analysis & characterization Vol. 24; no. 2; pp. 105 - 113
• Main Authors: Santuryan, Yu G., Malakhova, I. I., Gorshkov, N. I., Krasikov, V. D., Panarin, E. F.
• Format: Journal Article
• Language: English
• Published: Philadelphia Taylor & Francis Ltd 17.02.2019
• Subjects: Chemical synthesis; Chromatography; Control methods; Copolymerization; Copolymers; Formic acid; Inorganic acids

The method for preparation of copolymers of N-vinylpyrrolidone (VP) and N-vinylamine (VA) with high yield were developed; the method involves radical copolymerization of VP with N-vinylformamide(VFA) followed by the removal of formyl protecting group in the presence of inorganic acids. The optimal c...