A fermented milk drink with Umbu (Spondias tuberosa) pulp and whey is effective for weight gain and re-nutrition in malnourished: An in vivo study in mice and children

• Published in: Food research international Vol. 181; p. 114083
• Main Authors: Mendes, Gabriela da Rocha Lemos, Souza, Handray Fernandes de, Lopes, João Pedro Antunes, Rocha, Ana Carolina Santos, Faria, Raquel Borges, Santos, Fábio Ribeiro dos, Mesquita, Bruna Mara Aparecida de Carvalho de, Santos, Sérgio Henrique Sousa, Durães, Carla Adriana Ferreira, Ferreira, Sildimar Rodrigues, Boitrago, Sarah Caroline Oliveira de Souza, Leal, Jéssica Santos, Kamimura, Eliana Setsuko, Brandi, Igor Viana
• Format: Journal Article
• Language: English
• Published: Canada Elsevier Ltd 01.04.2024
• Subjects: Anacardiaceae; Animals; Anthropometry; Body Weight; Child; Dairy product; Dietary restriction; Humans; Malnutrition; Mice; Milk; Nutritional Status; Translational study; Weight Gain; Whey; Whey Proteins; Translational study; Dairy product; Dietary restriction; Malnutrition; Anthropometry
• ISSN: 0963-9969; 1873-7145
• DOI: 10.1016/j.foodres.2024.114083

[Display omitted] •Milk drink increased body weight by 7.2% and albumin by 64.3% in malnourished mice.•Contributes to a 35% reduction in cholesterol in malnourished mice.•It increased body weight by 16.5% in malnourished children.•It increased body mass index by 20.9% in malnourished children.•It has a positive effect on the re-nutrition of undernourished mice and children. Malnutrition is considered one of the major public health problems worldwide and negatively affects the growth, development and learning of schoolchildren. This study developed and evaluated a fermented milk drink with added Umbu (Spondias tuberosa) pulp in the weight gain and renutrition of mice submitted to malnutrition by calorie restriction, and in malnourished children. The supplementation with this fermented milk drink contributed to an increase of 7.2 % in body weight, and 64.3 % in albumin, and a reduction of 35 % in cholesterol in malnourished mice. In humans, a group of nine malnourished children consumed a daily 200 mL serving of the milk drink (for 60 days). For humans, the fermented milk drink allowed an increase of 16.5 % in body weight, and 20.9 % in body mass index in malnourished children. In conclusion, fermented milk drink has a positive effect on the re-nutrition of malnourished mice and helps to improve the nutritional status of malnourished children.