NM23/nucleoside diphosphate kinase and signal transduction

NM23s (or NDP kinases) regulate a fascinating variety of cellular activities, including proliferation, development, and differentiation. All these processes are modulated by external stimuli, leading to the idea that this family of proteins modulates transmembrane signaling pathways. This review sum...

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Bibliographic Details
Published inJournal of bioenergetics and biomembranes Vol. 32; no. 3; pp. 269 - 275
Main Author Otero, A S
Format Journal Article
LanguageEnglish
Published United States Springer Nature B.V 01.06.2000
Subjects
Animals
Biochemistry
Cells
Humans
Kinases
Monomeric GTP-Binding Proteins - metabolism
NM23 Nucleoside Diphosphate Kinases
Nucleoside-Diphosphate Kinase - metabolism
Signal Transduction
Transcription Factors - metabolism
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Summary:NM23s (or NDP kinases) regulate a fascinating variety of cellular activities, including proliferation, development, and differentiation. All these processes are modulated by external stimuli, leading to the idea that this family of proteins modulates transmembrane signaling pathways. This review summarizes the evidence indicating that NM23/NDP kinases participate in transmembrane signaling in eukaryotic cells and discusses the molecular mechanisms proposed to account for these actions.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0145-479X
1573-6881
DOI:10.1023/A:1005589029959