Repair of Wounds of the Mucosa in the Rectum of the Cat

Investigators of wound healing in the alimentary canal have carried out their experiments mainly in the gastro-duodenal region, in view of the importance of the problem of peptic ulceration in man. Little attention has been paid to repair processes at lower levels of the intestinal tract; histologic...

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Bibliographic Details
Published inDevelopment (Cambridge) Vol. 6; no. 3; pp. 509 - 517
Main Authors McMINN, R M, JOHNSON, F R
Format Journal Article
LanguageEnglish
Published England Oxford University Press for The Company of Biologists Limited 01.09.1958
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Summary:Investigators of wound healing in the alimentary canal have carried out their experiments mainly in the gastro-duodenal region, in view of the importance of the problem of peptic ulceration in man. Little attention has been paid to repair processes at lower levels of the intestinal tract; histological investigations on this subject in the large intestine appear to have been carried out only by O'Connor (1954, 1956) and by Lumb & Protheroe (1955). Sircus (1956) studied the ulceration that ensued in portions of colon that had been implanted into the stomach wall in dogs, but his interest lay in the mechanism of ulcer production rather than ulcer healing, and Truelove's (1957) biopsies from patients with ulcerative colitis were used largely to assess a method of treatment and not to investigate repair processes. The present series of experiments was carried out in order to study the repair of mucosal lesions in the rectum of the cat.
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ISSN:0950-1991
0022-0752
1477-9129
DOI:10.1242/dev.6.3.509