Orofacial granulomatosis A case report and a proposal of a diagnostic algorithm for oral granulomatous lesions

Orofacial granulomatosis (OFG) is an uncommon chronic inflammatory disorder with multifactorial etiology and pathogenesis affecting the orofacial region which appears usually as a persistent and/or recurrent swelling that may involve one or both the lips and/or recurrent ulcers along with other orof...

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Published inJournal of oral and maxillofacial pathology : JOMFP Vol. 25; no. 2; pp. 346 - 350
Main Authors Shetty, Nisha, Subramanyam, R, Srikanth, Gadicherla, Solomon, Monica
Format Journal Article
LanguageEnglish
Published India Medknow Publications and Media Pvt. Ltd 01.05.2021
Medknow Publications & Media Pvt Ltd
Subjects
Adalimumab
Algorithms
Case Report
Metronidazole
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Summary:Orofacial granulomatosis (OFG) is an uncommon chronic inflammatory disorder with multifactorial etiology and pathogenesis affecting the orofacial region which appears usually as a persistent and/or recurrent swelling that may involve one or both the lips and/or recurrent ulcers along with other orofacial features. The diagnosis of OFG is challenging and it should be ruled out from other conditions characterized by granulomatous inflammation. This article describes a case of a 30-year-old female patient with upper lip swelling as the main manifestation without any systemic involvement and we have also laid down a proposal of a diagnostic algorithm for differential diagnoses and treatment modalities for OFG which could be helpful for the clinician and dentists alike to rule out other granulomatous disorders thus in effective management of OFG.
ISSN:0973-029X
1998-393X
DOI:10.4103/0973-029X.325238