Anti-microbial and skin wound dressing application of molecular iodine nanoparticles

In this study, iodine nanoparticles were synthesized without use of any stabilizer by a new co-precipitation process using polyvinyl pyrolidone, calcium lactate, disodium hydrogen phosphate and iodine solution as precursor and the reaction was catalyzed by sodium hydroxide. Ten mg of the synthesized...

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Bibliographic Details
Published inMaterials research express Vol. 4; no. 10; pp. 104003 - 104009
Main Authors Viswanathan, Kaliyaperumal, Babu, Divya Bharathi, Jayakumar, Gomathi, Dhinakar Raj, Gopal
Format Journal Article
LanguageEnglish
Published IOP Publishing 24.10.2017
Subjects
bacteria
iodine
iodine nanoparticles
wound healing
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Summary:In this study, iodine nanoparticles were synthesized without use of any stabilizer by a new co-precipitation process using polyvinyl pyrolidone, calcium lactate, disodium hydrogen phosphate and iodine solution as precursor and the reaction was catalyzed by sodium hydroxide. Ten mg of the synthesized nanoparticles killed 95% of bacteria and inhibited 90% of bio film formation. Assays on membrane disintegration activities of the nanoparticles indicated that these nanoparticles destroyed the extracellular membrane of the bacteria. The wound healing application evaluated using mice model showed that it was hastened by iodine nanoparticles.
Bibliography:MRX-105172.R1
ISSN:2053-1591
2053-1591
DOI:10.1088/2053-1591/aa91e5