Use of plasma for immediate diagnosis of multiple sclerosis (plasma-erythrocyte unsaturated fatty acid test): comparison with the erythrocyte-unsaturated fatty acid (E-UFA) test

A labile factor in plasma (but not serum) of MS subjects confers MS like properties vis à vis effect of linoleic acid (LA) and arachidonic acid (AA), on the electrophoretic mobility of washed red blood cells (RBC) irrespective of their provenance. Plasma from anomalous MS relatives and other neurolo...

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Bibliographic Details
Published inNeurological research (New York) Vol. 8; no. 1; p. 57
Main Authors Field, E J, Joyce, G
Format Journal Article
LanguageEnglish
Published England 01.03.1986
Subjects
Arachidonic Acid
Arachidonic Acids - blood
Erythrocytes - analysis
Fatty Acids, Unsaturated - blood
Female
Humans
Linoleic Acid
Linoleic Acids - blood
Male
Multiple Sclerosis - blood
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Summary:A labile factor in plasma (but not serum) of MS subjects confers MS like properties vis à vis effect of linoleic acid (LA) and arachidonic acid (AA), on the electrophoretic mobility of washed red blood cells (RBC) irrespective of their provenance. Plasma from anomalous MS relatives and other neurological diseases (OND) likewise confer corresponding properties on washed RBC. The magnitude of results produced by LA and AA on plasma coated cells is equal to that produced by LA and AA directly on the original cells and approximately twice that reported with latex particles.
ISSN:0161-6412
DOI:10.1080/01616412.1986.11739732