Effect of Brown Algae Cystoseira trinodis Methanolic Extract on Renal Tissue

• Published in: Pharmaceutical Sciences Vol. 22; no. 1; pp. 49 - 53
• Main Authors: Gazor, Rouhollah, Pasdaran Lashgari, Ardalan, Almasi, Shabnam, Ghasemi, Saeed
• Format: Journal Article
• Language: English
• Published: Tabriz Tabriz University of Medical Sciences 01.03.2016
• Subjects: Algae; Antioxidants; Chemical compounds; Cystoseira trinodis; Food; Histopathological Effect; Histopathology; Injuries; Kidneys; Laboratory animals; methanolic extract; nephrotoxic effect; Pharmacy; Rodents; Studies; Iran; Germany
• ISSN: 2383-2886; 1735-403X; 2383-2886
• DOI: 10.15171/PS.2016.09

Some of the algae compounds have revealed biological and potential therapeutic properties such as anti-inflammatory, antibacterial, antiviral, cytotoxic and antimitotic activities.5-7 Among the chemical compounds, polyphenols, polysaccharides, meroterpenoids and terpenoids are the major chemical groups in the brown algae.8 Also many of these compounds such as carotenoids and natural pigments have valuable roles as the antioxidant in human health.9 However several chemical compounds such as terpenoids and steroids have been isolated from different species of the Cystoseira genus but limited histopathological studies about effects of algae extracts have been reported.10,11 Although many of the algae are used as food source and alternative health care remedies insufficient studies on adverse effects of them clearly necessitate more investigations about them. For this reason AKI studies are important related to many situations including natural chemical compounds toxicity. Because there is no data available about algae extract effects on renal tissue until now, we considered nephropathological effect of polar extract of one species of Cystoseira genus in this research.