Antioxidants in liver health

Liver diseases are a worldwide medical problem because the liver is the principal detoxifying organ and maintains metabolic homeostasis. The liver metabolizes various compounds that produce free radicals(FR).However, antioxidants scavenge FR and maintain the oxidative/antioxidative balance in the li...

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Published inWorld journal of gastrointestinal pharmacology and therapeutics Vol. 6; no. 3; pp. 59 - 72
Main Authors Casas-Grajales, Sael, Muriel, Pablo
Format Journal Article
LanguageEnglish
Published United States Baishideng Publishing Group Inc 06.08.2015
Subjects
Antioxidant
Coffee
Curcumin
diseases
Liver
Naringenin
Oxidative
Quercetin
Resveratrol
Review
Silymarin
stress
Oxidative stress
Liver diseases
Naringenin
Silymarin
Quercetin
Resveratrol
Curcumin
Antioxidant
Coffee
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Summary:Liver diseases are a worldwide medical problem because the liver is the principal detoxifying organ and maintains metabolic homeostasis. The liver metabolizes various compounds that produce free radicals(FR).However, antioxidants scavenge FR and maintain the oxidative/antioxidative balance in the liver. When the liver oxidative/antioxidative balance is disrupted, the state is termed oxidative stress. Oxidative stress leadsto deleterious processes in the liver and produces liver diseases. Therefore, restoring antioxidants is essential to maintain homeostasis. One method of restoring antioxidants is to consume natural compounds with antioxidant capacity. The objective of this review is to provide information pertaining to various antioxidants found in food that have demonstrated utility in improving liver diseases.
Bibliography:Sael Casas-Grajales;Pablo Muriel;Department of Phar-macology, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional
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Correspondence to: Pablo Muriel, PhD, Department of Pharmacology, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, D.F., C.P. 14-740, México City 07000, México. pmuriel@cinvestav.mx
Telephone: +52-55-57473303 Fax: +52-55-57473394
Author contributions: Both authors contributed to this paper.
ISSN:2150-5349
2150-5349
DOI:10.4292/wjgpt.v6.i3.59