Unifocal bone paracoccidioidomycosis, Brazil

We report a 47 year-old man from the State of Mato Grosso do Sul, Brazil, with unifocal tibial paracoccidioidomycosis. A radiograph showed an osteolytic lesion on the tibial middle third diaphysis. The diagnosis was confirmed by histopathologic analysis, and treatment with sulfamethoxazole and trime...

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Bibliographic Details
Published inThe American journal of tropical medicine and hygiene Vol. 86; no. 3; pp. 470 - 473
Main Authors Correa-de-Castro, Bruna, Pompilio, Mauricio A, Odashiro, Danilo N, Odashiro, Maçanori, Arão-Filho, Adalberto, Paniago, Anamaria M M
Format Journal Article
LanguageEnglish
Published United States The American Society of Tropical Medicine and Hygiene 01.03.2012
SeriesCase Report
Subjects
Bone Diseases, Infectious - microbiology
Brazil - epidemiology
Humans
Male
Middle Aged
Paracoccidioides - pathogenicity
Paracoccidioides brasiliensis
Paracoccidioidomycosis - diagnostic imaging
Paracoccidioidomycosis - drug therapy
Paracoccidioidomycosis - epidemiology
Radiography
Tibia - microbiology
Tibia - pathology
Treatment Outcome
Brazil
Brazil, Mato Grosso do Sul
Latin America
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Summary:We report a 47 year-old man from the State of Mato Grosso do Sul, Brazil, with unifocal tibial paracoccidioidomycosis. A radiograph showed an osteolytic lesion on the tibial middle third diaphysis. The diagnosis was confirmed by histopathologic analysis, and treatment with sulfamethoxazole and trimethoprim was started. After three months, the patient showed significant clinical improvement. Ten months after treatment, the patient showed lesion bone healing. This case describes the rare occurrence of an osteolytic lesion caused by endemic Paracoccidioides brasiliensis in Latin America.
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ISSN:0002-9637
1476-1645
DOI:10.4269/ajtmh.2012.11-0295