Troponin

Cardiac troponin (cTn) is a biomarker of myocardial damage. New generations of high-sensitivity assays find circulating cTn in virtually all subjects. Multiple studies in various populations and patient groups have found higher levels of cTn to be predictive of future heart failure. The author propo...

Full description

Saved in:
Bibliographic Details
Published inJournal of the American College of Cardiology Vol. 61; no. 6; pp. 611 - 614
Main Author Popp, Richard L.
Format Journal Article
LanguageEnglish
Published New York Elsevier Inc 12.02.2013
Elsevier Limited
Subjects
Acute coronary syndromes
autoimmunity
Biomarkers
Cardiology
Cardiovascular
Heart attacks
Heart failure
Ischemia
Rheumatoid arthritis
Rodents
Surgery
troponin
heart failure
CV
autoimmunity
troponin
biomarkers
cTn
MI
cardiac troponin
myocardial infarction
coefficient of variation
Online AccessGet full text

Cover

More Information
Summary:Cardiac troponin (cTn) is a biomarker of myocardial damage. New generations of high-sensitivity assays find circulating cTn in virtually all subjects. Multiple studies in various populations and patient groups have found higher levels of cTn to be predictive of future heart failure. The author proposes that initial myocardial damage from various mechanisms may lead to anti-cTn antibodies that participate in ongoing myocardial damage that eventually results in heart failure.
Bibliography:SourceType-Scholarly Journals-1
ObjectType-Commentary-1
content type line 14
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2012.11.024