Use of lipid-modulating drugs in complicated course of coronary heart disease

We present the results of the study of lipid-modulating drugs (pravastatin, atorvastatin, simvastatin, and fibrate gemfibrozil) in complicated coronary heart disease (acute coronary syndrome without ST elevation, chronic heart failure. In acute coronary syndrome statins produced a positive effect on...

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Bibliographic Details
Published inBulletin of experimental biology and medicine Vol. 144; no. 3; pp. 438 - 446
Main Authors Gratsianskii, N A, Vaulin, N A
Format Journal Article
LanguageEnglish
Published United States Springer Nature B.V 01.09.2007
Subjects
Antithrombin III - metabolism
Atorvastatin
Cholesterol, LDL - metabolism
Coronary Disease - drug therapy
Echocardiography
Female
Gemfibrozil - therapeutic use
Heptanoic Acids - therapeutic use
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use
Hypolipidemic Agents - therapeutic use
Male
Peptide Hydrolases - metabolism
Pravastatin - therapeutic use
Prothrombin - metabolism
Pyrroles - therapeutic use
Simvastatin - therapeutic use
von Willebrand Factor - metabolism
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Summary:We present the results of the study of lipid-modulating drugs (pravastatin, atorvastatin, simvastatin, and fibrate gemfibrozil) in complicated coronary heart disease (acute coronary syndrome without ST elevation, chronic heart failure. In acute coronary syndrome statins produced a positive effect on some studied parameters, while in heart failure only the safety of short-term therapy with statins was demonstrated.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
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ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-007-0348-8