Clinicopathologic features of primary intraosseous carcinoma in situ arising from odontogenic keratocyst: A case report and literature review

The primary intraosseous carcinoma (PIOC) arising from an odontogenic keratocyst (OKC) is an exceedingly rare entity with only about 30 documented cases over the past eight decades. Although there have been documented cases in literature, few actually describe early carcinomatous change within benig...

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Published inJournal of oral and maxillofacial surgery, medicine, and pathology Vol. 33; no. 3; pp. 354 - 357
Main Authors Toh, Aileen Qiu Jin, Khoo, Ui-Soon, Choi, Wing Shan, Su, Yu-Xiong
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 01.05.2021
Subjects
Odontogenic keratocyst
Primary intraosseous carcinoma
Primary intraosseous carcinoma
Odontogenic keratocyst
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Summary:The primary intraosseous carcinoma (PIOC) arising from an odontogenic keratocyst (OKC) is an exceedingly rare entity with only about 30 documented cases over the past eight decades. Although there have been documented cases in literature, few actually describe early carcinomatous change within benign cyst epithelial lining. We present a case of PIOC in situ arising from an OKC in a 54 year-old female, providing histological evidence of early transition of benign cyst epithelial lining into squamous cell carcinoma.
ISSN:2212-5558
2212-5566
DOI:10.1016/j.ajoms.2020.11.004