Modulating the antibacterial activity of gold nanoparticles by balancing their monodispersity and aggregation

• Published in: Chemical communications (Cambridge, England) Vol. 58; no. 55; pp. 769 - 7693
• Main Authors: Wang, Le, Zheng, Wenfu, Li, Sixiang, Hou, Qinghong, Jiang, Xingyu
• Format: Journal Article
• Language: English
• Published: Cambridge Royal Society of Chemistry 07.07.2022
• Subjects: Agglomeration; antibacterial properties; chemical communication; exhibitions; Gold; nanogold; Nanoparticles; particles; Shielding

Aggregation is a key factor influencing the function of nanoparticles. Thioproline-modified gold nanoparticles show potent antibacterial activity, which is compromised by thioproline-mediated particle aggregation. By tuning the balance between the exposure and shielding of thioproline, a maximal ant...