Systemic toxicity of topical cyclopentolate eyedrops in a child

An 8 year old girl was seen in our ophthalmology OPD who had come with complains of mild pain in both eyes since 1 month. Her unaided vision in both eyes was 6/6. Her weight was 20 kilogram. Cyclopentolate 1% was administered twice to the child at 5 minutes interval. Child became restless after 30 m...

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Bibliographic Details
Published inTNOA Journal of Ophthalmic Science and Research Vol. 60; no. 1; pp. 96 - 97
Main Author Ashok, Abhinay
Format Journal Article
LanguageEnglish
Published Wolters Kluwer India Pvt. Ltd 01.01.2022
Medknow Publications and Media Pvt. Ltd
Wolters Kluwer Medknow Publications
Subjects
adverse effects
central nervous system side effects
cyclopentolate
dilating drops
Ophthalmic drugs
Ophthalmology
Adverse effects
central nervous system side effects
dilating drops
cyclopentolate
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Summary:An 8 year old girl was seen in our ophthalmology OPD who had come with complains of mild pain in both eyes since 1 month. Her unaided vision in both eyes was 6/6. Her weight was 20 kilogram. Cyclopentolate 1% was administered twice to the child at 5 minutes interval. Child became restless after 30 minutes of installation of eye drops; she started behaving abnormally and was not allowing to do retinoscopic examination. She had altered behavior, visual hallucination and difficulty in walking. She was disoriented with slurred speech. She had ataxia and frequent tightening of limbs with jerky movements and was plucking her hair. Her pulse rate was 90/minute and blood pressure was 120/90 mm of Hg. Her oxygen saturation was 94% in room air. Child was shifted to nearby hospital where a pediatrician and anesthesiologist were available and was kept under observation. Childs pulse, blood pressure and oxygen saturation were monitored for the next 5 hours. Child recovered completely over the next 8 hours.
ISSN:2589-4528
2589-4536
2589-4528
DOI:10.4103/tjosr.tjosr_59_21