Laparoscopic indocyanine green fluorescence imaging technique in rare type II cystic biliary atresia

• Published in: Photodiagnosis and photodynamic therapy Vol. 44; p. 103846
• Main Authors: Wang, Murong, Liao, Junmin, Li, Shuangshuang, Zhang, Shouhua, Huang, Jinshi
• Format: Journal Article
• Language: English
• Published: Netherlands 01.12.2023
• Subjects: Bile Acids and Salts; Biliary Atresia - diagnostic imaging; Biliary Atresia - surgery; Bilirubin; Choledochal Cyst - diagnostic imaging; Choledochal Cyst - surgery; Female; Humans; Indocyanine Green; Laparoscopy - methods; Optical Imaging; Photochemotherapy - methods; Photosensitizing Agents; Optical imaging; Biliary atresia; Indocyanine green; Cysts; Surgery; Cholestasis
• ISSN: 1572-1000; 1873-1597
• DOI: 10.1016/j.pdpdt.2023.103846

In recent years, it has been reported that indocyanine green can be used for intraoperative navigation in Kasai surgery. However, there are no reports of its application in surgery for rare type II cystic biliary atresia. We report a girl presented with jaundice and light-colored stools. Laboratory tests showed impaired liver function with elevated serum bilirubin and bile acid levels. The abdominal ultrasound and MRCP suggested a common hepatic duct cyst. A diagnosis of choledochal cyst was suspected and biliary atresia could not be excluded. Conservative treatment was unsatisfactory. Laparoscopic exploration with indocyanine green fluorescence was performed on the 38th day of her life, and intraoperative diagnosis of type II CBA was made because the common hepatic duct cyst and its downstream anatomical structures did not show fluorescence. The postoperative bilirubin and bile acid levels decreased significantly and she was discharged two weeks after surgery. This result suggests that indocyanine green can be safely used in laparoscopic surgery for type II CBA, which not only helps in the differential diagnosis of CBA and choledochal cyst, but also confirms bile flow in real time.