Intensity-modulated radiation therapy in gynecologic malignancies

Radiation therapy (RT) is commonly used in the treatment of gynecologic malignancies. Unfortunately, RT exposes patients to a wide variety of sequelae. Concerns over toxicity also limit the use of higher doses in select patients. To improve the efficacy of conventional RT and to explore the possibil...

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Bibliographic Details
Published inMedical dosimetry : official journal of the American Association of Medical Dosimetrists Vol. 27; no. 2; p. 131
Main Authors Mundt, Arno J, Roeske, John C, Lujan, Anthony E
Format Journal Article
LanguageEnglish
Published United States 2002
Subjects
Dose-Response Relationship, Radiation
Female
Genital Neoplasms, Female - diagnostic imaging
Genital Neoplasms, Female - radiotherapy
Humans
Radiotherapy Planning, Computer-Assisted
Radiotherapy, Conformal
Tomography, X-Ray Computed
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Summary:Radiation therapy (RT) is commonly used in the treatment of gynecologic malignancies. Unfortunately, RT exposes patients to a wide variety of sequelae. Concerns over toxicity also limit the use of higher doses in select patients. To improve the efficacy of conventional RT and to explore the possibility of dose escalation, we have turned to the use of intensity-modulated RT (IMRT). This report reviews our preclinical studies, implementation, and clinical experience to date with IMRT for gynecologic malignancies.
ISSN:0958-3947
1873-4022
DOI:10.1016/S0958-3947(02)00095-X