Characterisation of the third component of canine and feline complement

Canine and feline C3 have been found by immune precipitation to have a molecular weight of 198K and 197K respectively. Each comprises two polypeptide chains α and β (canine α - 126K β - 72K; feline α - 125K β - 72K). The α chain is subsequently cleaved by C3b ina to produce two fragments α edc (cani...

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Bibliographic Details
Published inVeterinary immunology and immunopathology Vol. 2; no. 4; pp. 309 - 320
Main Authors Gorman, N.T., McConnell, I., Lachmann, P.J.
Format Journal Article
LanguageEnglish
Published Elsevier B.V 1981
Subjects
animal health
veterinary medicine
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Summary:Canine and feline C3 have been found by immune precipitation to have a molecular weight of 198K and 197K respectively. Each comprises two polypeptide chains α and β (canine α - 126K β - 72K; feline α - 125K β - 72K). The α chain is subsequently cleaved by C3b ina to produce two fragments α edc (canine 65K; feline 64K) and α fb (canine 40K; feline 46K). The findings are compared to the documented molecular structure of human C3.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
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ISSN:0165-2427
1873-2534
DOI:10.1016/0165-2427(81)90053-2