Nangallenes A and B, halogenated nonterpenoid C-15-acetogenins from the Bornean red alga Laurencia nangii

Two new halogenated nonterpenoids C-15-acetogenins, nangallenes A-B (1-2), together with two known halogenated compounds itomanallene A (3) and 2,10-dibromo-3-chloro-alpha-chamigrene (4), were isolated and identified from the organic extract of the marine red alga Laurencia nangii Masuda collected f...

Full description

Saved in:
Bibliographic Details
Published inJournal of asian natural products research Vol. 21; no. 3; pp. 241 - 247
Main Authors Kamada, Takashi, Chin-Soon Phan, Vairappan, Charles S.
Format Journal Article
LanguageEnglish
Published ABINGDON Taylor & Francis 04.03.2019
Subjects
Chemistry
Chemistry, Applied
Chemistry, Medicinal
Life Sciences & Biomedicine
Pharmacology & Pharmacy
Physical Sciences
Plant Sciences
Science & Technology
Borneo
METABOLITES
red alga
C-15-acetogenin
halogenated compound
Rhodomelaceae
CHEMISTRY
Laurencia nangii
ACETOGENINS
C-acetogenin
Online AccessGet full text

Cover

More Information
Summary:Two new halogenated nonterpenoids C-15-acetogenins, nangallenes A-B (1-2), together with two known halogenated compounds itomanallene A (3) and 2,10-dibromo-3-chloro-alpha-chamigrene (4), were isolated and identified from the organic extract of the marine red alga Laurencia nangii Masuda collected from the coastal waters in Semporna, Borneo. Their structures were established by means of spectroscopic analysis including IR, high-resolution electrospray ionization mass spectrometry (HRESI-MS), and 1D and 2D NMR techniques. All these metabolites were submitted for the antifungal assay against four species of selected marine fungi. Compounds 1-4 showed potent activity against Haliphthoros sabahensis and Lagenidium thermophilum.
ISSN:1028-6020
1477-2213
DOI:10.1080/10286020.2017.1417265