Oral candidiasis in patients with kidney transplantation in Iran: prevalence and antifungal susceptibility pattern

This study aimed to identify species recovered from the oral cavity of patients with kidney transplantation. Two swabs were taken from the oral cavities of 40 patients before and after transplantation, cultured on Sabouraud dextrose agar, and yeasts identified. Antifungal drug susceptibility testing...

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Published inFuture microbiology Vol. 18; no. 11; pp. 715 - 722
Main Authors Ghadimi, Fardad, Rodrigues, Célia F, Mohammadi, Shahla Roudbar, Roudbary, Maryam, dos Santos, André LS, Aslani, Peyman, Nikoomanesh, Fatemeh
Format Journal Article
LanguageEnglish
Published Future Medicine Ltd 01.07.2023
Subjects
antifungal drug susceptibility
kidney transplant
molecular identification
oral candidiasis
species
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Summary:This study aimed to identify species recovered from the oral cavity of patients with kidney transplantation. Two swabs were taken from the oral cavities of 40 patients before and after transplantation, cultured on Sabouraud dextrose agar, and yeasts identified. Antifungal drug susceptibility testing was performed with fluconazole and itraconazole. was the most frequently isolated species in patients, followed by and . isolates from patients before transplantation were resistant to fluconazole, whereas was fluconazole-resistant both before and after transplantation. The importance of non species in the oral cavity of patients sheds light on performing antifungal tests for achieving the best outcome to prevent therapeutic failure.
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ISSN:1746-0913
1746-0921
DOI:10.2217/fmb-2022-0179