Two new bufotoxins from the skin of Bufo bufo gargarizans

• Published in: Chinese chemical letters Vol. 24; no. 8; pp. 731 - 733
• Main Authors: Li, Hai-Yan, Zhang, Lian-Zhu, Wang, Shi-Hui, Deng, Yue, Jin, Xiang-Qun
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.08.2013; Affiliated Hospital of Changchun University of Chinese Medicine, Changchun 130021, China; College of Pharmaceutical Sciences, Jilin University, Changchun 130021, China%Affiliated Hospital of Changchun University of Chinese Medicine, Changchun 130021, China%College of Pharmaceutical Sciences, Jilin University, Changchun 130021, China
• Subjects: Bufo bufo gargarizans; Bufotoxins; Tolocinobufagin-3-hemisuberate; Tolocinobufagin-3-succinoylarginine; 中华大蟾蜍; 分离; 天然来源; 皮肤; 谱方法; Tolocinobufagin-3-hemisuberate; Bufo bufo gargarizans; Bufotoxins; Tolocinobufagin-3-succinoylarginine
• ISSN: 1001-8417; 1878-5964
• DOI: 10.1016/j.cclet.2013.04.044

Two new bufotoxins,tolocinobufagin-3-succinoylarginine ester and tolocinobufagin-3-hemisuberate, were isolated from the skin of Bufo bufo gargarizans Cantor.Cinobufagin-3-hemisuberate was also isolated from the natural source for the first time.Their structures were established using spectroscopic methods.