Central nervous system tuberculoma mimicking a brain tumor: A case report

The central nervous system (CNS) is a rare but serious site of tuberculosis spread that manifests in three forms: meningitis, spinal arachnoiditis, and CNS tuberculoma. CNS tuberculoma, or intracranial tuberculous granuloma, is a caseating or non-caseating granulomatous reaction within the brain par...

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Published inRadiology case reports Vol. 19; no. 1; pp. 414 - 417
Main Authors McMahon, Pierce, Pisapia, David J., Schweitzer, Andrew D., Heier, Linda, Souweidane, Mark M., Roytman, Michelle
Format Journal Article
LanguageEnglish
Published Elsevier 01.01.2024
Subjects
Central Nervous System (CNS)
Tuberculoma
Tuberculosis
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Summary:The central nervous system (CNS) is a rare but serious site of tuberculosis spread that manifests in three forms: meningitis, spinal arachnoiditis, and CNS tuberculoma. CNS tuberculoma, or intracranial tuberculous granuloma, is a caseating or non-caseating granulomatous reaction within the brain parenchyma that may mimic a brain tumor. We present the case of a 10-year-old male patient with a travel history to Western Africa who presented to our institution after his fourth tonic-clonic seizure over 2 months. MRI of the brain revealed a solitary cortical/subcortical enhancing intracranial mass with intralesional hemorrhage and mineralization, pathologically proven to represent a CNS tuberculoma. While rare, this etiology should be considered with the appropriate travel history and for which prompt treatment may improve outcomes in the pediatric population.
ISSN:1930-0433
1930-0433
DOI:10.1016/j.radcr.2023.10.042