Comparative Activities of Cattle and Swine Platelet Microbicidal Proteins

The bactericidal activities of cattle and swine platelet microbicidal proteins (PMPs) with their comparison with human PMP were studied. Activities of PMP were tested against Bacillus subtilis, Bacillus cereus, Staphylococcus aureus, Staphylococcus epidermidis, Micrococcus lysodeikticus and Escheric...

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Published inProbiotics and antimicrobial proteins Vol. 1; no. 2; pp. 148 - 151
Main Authors Ivanov, Iuri B., Gritsenko, Viktor A.
Format Journal Article
LanguageEnglish
Published New York Springer-Verlag 01.12.2009
Subjects
Applied Microbiology
Chemistry
Chemistry and Materials Science
Chemistry/Food Science
Microbiology
Nutrition
Protein Science
Swine
Platelet microbicidal protein
Cow
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Summary:The bactericidal activities of cattle and swine platelet microbicidal proteins (PMPs) with their comparison with human PMP were studied. Activities of PMP were tested against Bacillus subtilis, Bacillus cereus, Staphylococcus aureus, Staphylococcus epidermidis, Micrococcus lysodeikticus and Escherichia coli. B. subtilis and B. cereus were high susceptible to PMP at very low concentrations. Of the gram-positive cocci studied, M. lysodeikticus and S. aureus were the most, and S. epidermidis the least, susceptible. E. coli was found to be relatively resistant to the lethal action of all PMP. The findings of this study confirm that the existence of antimicrobial peptides is conserved among mammalian platelets.
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ISSN:1867-1306
1867-1314
DOI:10.1007/s12602-009-9016-9