Oral involvement of cutaneous T-cell lymphoma: A rare entity

Mycosis fungoides (MF) is a rare cutaneous T-cell lymphoma (CTCL) with significant morbidity and mortality rates. Involvement of MF in the oral cavity is uncommon, often follows cutaneous involvement, and is usually associated with a poor prognosis. Herein, we describe a case of a 72-year-old White...

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Published inOral surgery, oral medicine, oral pathology and oral radiology Vol. 135; no. 5; pp. e102 - e107
Main Authors Mahajan, Roopali, Davila, Andres, Alawi, Faizan, Tanaka, Takako I., Stoopler, Eric T., Sollecito, Thomas P.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.05.2023
Subjects
Aged
Biopsy
Disease Progression
Humans
Lymphoma, T-Cell, Cutaneous - diagnosis
Lymphoma, T-Cell, Cutaneous - pathology
Male
Mycosis Fungoides - diagnosis
Mycosis Fungoides - pathology
Skin Neoplasms - pathology
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Summary:Mycosis fungoides (MF) is a rare cutaneous T-cell lymphoma (CTCL) with significant morbidity and mortality rates. Involvement of MF in the oral cavity is uncommon, often follows cutaneous involvement, and is usually associated with a poor prognosis. Herein, we describe a case of a 72-year-old White male with biopsy-proven oral T-cell lymphoma (TCL) in the setting of MF with systemic disease progression. Mycosis fungoides with oral involvement can often prove challenging to diagnose and manage. Thorough medical history intake and clinical examination supported by histopathologic and immunohistochemical analysis are imperative because delay in the diagnosis can lead to disease progression.
ISSN:2212-4403
2212-4411
DOI:10.1016/j.oooo.2022.12.006