Microarrays meet the Voltaire challenge: Drug discovery on a chip?

The co-emergence of microarray technologies with systems oriented approaches to discovery is testament to the technological and conceptual advancements of recent years. By providing a platform for massively parallelized reductionism, microarrays are enabling us to examine the functional features of...

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Published inDrug discovery today. Technologies Vol. 3; no. 2; pp. 153 - 161
Main Authors Jackson, David B., Stein, Martin A., Merino, Alejandro, Eils, Roland
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 2006
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Summary:The co-emergence of microarray technologies with systems oriented approaches to discovery is testament to the technological and conceptual advancements of recent years. By providing a platform for massively parallelized reductionism, microarrays are enabling us to examine the functional features of diverse classes of bio-system components in a contextually meaningful manner. Yet, to provide economic impact, future development of these technologies demands intimate alignment with the goal of producing safer and more efficacious drugs. Andreas Russ – University of Oxford, Oxford, UK
Bibliography:ObjectType-Article-1
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ISSN:1740-6749
1740-6749
DOI:10.1016/j.ddtec.2006.06.014