Viral tissue tropisms and interferon production in White Leghorn chickens infected with two avian reovirus strains

Inoculation of 6-day-old and 4-week-old chickens with pathogenic or attenuated avian reovirus resulted in an inapparent infection. The virus had a greater tissue distribution and persisted longer in tissues of 6-day-old chickens. Interferon was detected in only the serum and lung of infected chicken...

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Bibliographic Details
Published inAvian diseases Vol. 27; no. 3; p. 644
Main Authors Ellis, M N, Eidson, C S, Fletcher, O J, Kleven, S H
Format Journal Article
LanguageEnglish
Published United States 01.07.1983
Subjects
Age Factors
Animals
Chickens
Interferons - biosynthesis
Organ Specificity
Poultry Diseases - metabolism
Poultry Diseases - microbiology
Reoviridae - growth & development
Reoviridae - isolation & purification
Reoviridae - pathogenicity
Reoviridae Infections - metabolism
Reoviridae Infections - microbiology
Reoviridae Infections - veterinary
Virulence
Virus Replication
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Summary:Inoculation of 6-day-old and 4-week-old chickens with pathogenic or attenuated avian reovirus resulted in an inapparent infection. The virus had a greater tissue distribution and persisted longer in tissues of 6-day-old chickens. Interferon was detected in only the serum and lung of infected chickens and appeared to be related to route of inoculation. Titers of interferon were greater and appeared sooner in the tissues of older chickens. Reovirus-neutralizing antibody was not detected in the serum of chickens of either age 120 days postinfection.
Bibliography:L
L73
ISSN:0005-2086
1938-4351
DOI:10.2307/1590306