Photonuclear production and radiochemical separation of medically relevant radionuclides: 67Cu

• Published in: Journal of radioanalytical and nuclear chemistry Vol. 321; no. 1; pp. 125 - 132
• Main Authors: Aliev, Ramiz A., Belyshev, Sergey S., Kuznetsov, Alexander A., Dzhilavyan, Leonid Z., Khankin, Vadim V., Aleshin, Gleb Yu, Kazakov, Andrey G., Priselkova, Anna B., Kalmykov, Stepan N., Ishkhanov, Boris S.
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 15.07.2019; Springer Nature B.V
• Subjects: Bremsstrahlung; Chemical reactions; Chemical separation; Chemistry; Chemistry and Materials Science; Diagnostic Radiology; Hadrons; Heavy Ions; Inorganic Chemistry; Irradiation; Nuclear Chemistry; Nuclear Physics; Organic chemistry; Photons; Photonuclear reactions; Physical Chemistry; Radiochemical separation; Radioisotopes; Statistical models; Zinc; Radionuclide therapy; Copper-67; Extraction chromatography; Photonuclear reactions
• ISSN: 0236-5731; 1588-2780
• DOI: 10.1007/s10967-019-06576-9

Production of medical radionuclide 67 Cu by the irradiation of Zn of natural isotopic composition by bremsstrahlung photons of maximum energy of 55 MeV was studied. Production yields of 67 Cu and other activation products were determined. The yield of 67 Cu is (2.34 ± 0.07) × 10 5  Bq/(μA h g/cm 2 ) at EOB. The experimental data were compared with the results of other experiments and theoretical calculations based on the statistical model in the TALYS software and on the combined model of photonuclear reactions. Technique of chemical separation of 67 Cu from irradiated zinc target based on extraction chromatography using CU Resin was applied. Radiochemical yield was > 95%, separation time was 1 h. The possibility of production of medical quantities was discussed.