A case of IgA nephropathy associated with adeno- and herpes simplex viruses

We report here an adult case of IgA nephropathy associated with episodes of recurrent tonsillitis. Various kinds of viral antigens were examined in the renal and tonsillar tissues by immunofluorescence. Granular depositions of adeno- and herpes simplex viral antigens were detected in the glomerular...

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Bibliographic Details
Published inNephron (2015) Vol. 47; no. 4; p. 258
Main Authors Tomino, Y, Yagame, M, Omata, F, Nomoto, Y, Sakai, H
Format Journal Article
LanguageEnglish
Published Switzerland 1987
Subjects
Adenoviruses, Human - immunology
Adult
Antigens, Viral - analysis
Female
Glomerulonephritis, IGA - etiology
Glomerulonephritis, IGA - immunology
Humans
Kidney Glomerulus - immunology
Kidney Glomerulus - microbiology
Palatine Tonsil - immunology
Palatine Tonsil - microbiology
Simplexvirus - immunology
Tonsillitis - complications
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Summary:We report here an adult case of IgA nephropathy associated with episodes of recurrent tonsillitis. Various kinds of viral antigens were examined in the renal and tonsillar tissues by immunofluorescence. Granular depositions of adeno- and herpes simplex viral antigens were detected in the glomerular mesangial areas and in the tonsillar epithelial cells by immunofluorescence. IgA and IgA1 deposits were also observed in the glomerular mesangial areas. It was suggested that IgA nephropathy might be caused by multiple antigenic substances, including adeno- and/or herpes simplex viruses, located in the tonsillar regions.
ISSN:1660-8151
2235-3186
DOI:10.1159/000184520